Depression and Stroke

Depression can strike anyone, but people with serious illnesses such as stroke may be at greater risk. Appropriate diagnosis and treatment of depression may bring substantial benefits to persons recovering from a stroke by improving their medical status, enhancing their quality of life, and reducing their pain and disability. Treatment for depression also can shorten the rehabilitation process, lead to more rapid recovery and resumption of routine, and save health care costs (e.g., eliminate nursing home expenses).

Stroke can occur in all age groups and can happen even to fetuses still in the womb; but three-fourths of strokes occur in people 65 years of age and over, making stroke a leading cause of disability in older persons. Of the 600,000 American men and women who experience a first or recurrent stroke each year, an estimated 10 to 27 percent experience major depression. An additional 15 to 40 percent experience some symptoms of depression within 2 months following a stroke.

The average duration of major depression in people who have suffered a stroke is just under a year. Among the factors that affect the likelihood and severity of depression following a stroke are the location of the brain lesion, previous or family history of depression, and pre-stroke social functioning. Stroke survivors who are also depressed, particularly those with major depressive disorder, may be less compliant with rehabilitation, more irritable, and may experience personality change.

Despite the enormous advances in brain research in the past 20 years, depression often goes undiagnosed and untreated. Stroke survivors, their family members and friends, and even their physicians may misinterpret depressive symptoms as an inevitable reaction to the effects of a stroke. But depression is a separate illness that can and should be treated, even when a person is undergoing post-stroke rehabilitation. Although depressive symptoms may overlap with post-stroke symptoms, skilled health professionals will recognize the symptoms of depression and inquire about their duration and severity, diagnose the disorder, and suggest appropriate treatment.

Stroke Facts

A stroke occurs when the blood supply to part of the brain is suddenly interrupted or when a blood vessel in the brain bursts, spilling blood into the spaces surrounding brain cells. Symptoms of stroke appear suddenly and often there is more than one symptom at the same time:

  • Sudden numbness or weakness of the face, arm, or leg, especially on one side of the body
  • Sudden confusion, trouble talking, or understanding speech
  • Sudden trouble seeing in one or both eyes
  • Sudden trouble walking, dizziness, or loss of balance or coordination
  • Sudden severe headache with no known cause

The most important risk factors for stroke are hypertension, heart disease, diabetes, and cigarette smoking. Others include heavy alcohol consumption, high blood cholesterol levels, illicit drug use, and genetic or congenital conditions, particularly vascular abnormalities.

Gender also plays a role in risk for stroke. Men have a higher risk for stroke, but since men do not live as long as women, women are generally older when they have strokes and are more likely to die from them. However, women’s hormonal changes during pregnancy, childbirth, and menopause increase their risk for stroke. The risk of stroke associated with pregnancy is greatest in the postpartum period—the 6 weeks following childbirth. Risk for stroke also varies among different ethnic and racial groups.

Although stroke is a disease of the brain, it can affect the entire body. Some of the disabilities that can result from a stroke include paralysis, cognitive deficits, speech problems, emotional difficulties, fatigue, and daily living problems. Many people require psychological or psychiatric help after a stroke. Depression, anxiety, frustration and anger are common post-stroke disabilities. Because stroke survivors often have complex rehabilitation needs, progress and recovery are unique for each person. Although a majority of functional abilities may be restored soon after a stroke, recovery is an ongoing process.

Treating Depression

Depression can affect mind, mood, body, and behavior. While there are many different treatments for depression, they must be carefully chosen by a trained professional based on the circumstances of the person and family. Prescription antidepressant medications are generally well-tolerated and safe for people recovering from a stroke. There are, however, possible interactions among some medications and side effects that require careful monitoring. Therefore, stroke survivors who develop depression, as well as people in treatment for depression who subsequently suffer a stroke, should make sure to tell any physician they visit about the full range of medications they are taking.

Specific types of psychotherapy, or “talk” therapy, also can relieve depression. Sometimes it is beneficial for family members of a stroke survivor to seek counseling as well.

(This is taken from NIH Publication No. 02-5006)

See articles in the cures for depression section for more information on treatments.

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